How do the requirements for a hypothesis generator in public health outbreak response often differ from those in drug discovery regarding evidence weighting?

Answer

The acceptable threshold for uncertainty and the weighting assigned to evidence types vary dramatically between the two applications.

While fundamental concepts might be shared, the weighting assigned to different evidence types and the acceptable threshold for uncertainty differ significantly between generating a targeted molecular proposal (drug discovery) and reacting to sparse, time-sensitive data (outbreak response).

How do the requirements for a hypothesis generator in public health outbreak response often differ from those in drug discovery regarding evidence weighting?
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