What are significant indicators that a job situation has crossed into being genuinely detrimental?

Answer

Experiencing chronic stress, difficulty sleeping, or increased reliance on unhealthy coping mechanisms

Significant indicators of detriment include physical and mental health manifestations like chronic stress, trouble sleeping, or needing unhealthy coping methods just to manage the week.

What are significant indicators that a job situation has crossed into being genuinely detrimental?
jobcareerworkdecisionunhappiness